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ImageXpress® Micro 4 High-Content Imaging System

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Configurable, high-throughput widefield imaging solution for an incredible range of assays

Widefield imaging for basic research through to high-content screening

The ImageXpress® Micro 4 High-Content Imaging System is a high-throughput, widefield imager that can acquire images of whole organisms and cellular or intracellular events. It features proprietary fast frame rate technology, allowing for the capture of fast biological processes such as calcium oscillations in cardiomyocytes. It is highly configurable and adaptable to changing research needs. Available options include confocal, brightfield, phase contrast, liquid handing, and environmental control.

  • Support many cellular assays

    Image an incredible range of assays with various user-changeable filter cubes, 1-100x objectives, environmental control, fluidics option, and many sample formats including atypical plates for 3D assays.

  • Analyze images of more applications

    A selection of feature-rich turnkey application modules is available with MetaXpress® software. For the development of novel assays, we offer an optional custom analysis module.

  • Tailor the system to meet your needs

    The imager is a highly flexible solution, you can add or change many of the components as your research priorities change. Examples include enhance light engines and automation.

 

Features

  • Multiple imaging modes

    The system offers fluorescence, widefield, colorimetric, phase contrast, and brightfield label-free imaging.

  • Upgradeable to confocal

    The system can be upgraded to include the proprietary AgileOptix™ technology for accurate 3D volumetric analyses.

  • Wide dynamic range

    Low and high intensity signal quantification in a single image with >3 log dynamic range intensity detection.

  • High speed image acquisition

    Using 4x magnification with a 1536-well plate, 225K wells per day can be acquired. Greater than a million wells per week can be imaged.

  • Optional environmental control

    Temperature, humidity, and CO2 control for multi-day live-cell imaging or fast kinetic studies are available.

  • Large magnification range

    Air and oil immersion objectives ranging from 1x to 100x are available for installation into the 4-position objective changer.

Widefield imaging for basic research through to high-content screening The ImageXpress Micro 4 High-Content Imaging System is a high-throughput, widefield imager that can acquire images of whole organisms and cellular or intracellular events. It features proprietary fast frame rate technology, allowing for the capture of fast biological processes such as calcium oscillations in cardiomyocytes. It is highly configurable and adaptable to changing research needs. Available options include confocal, brightfield, phase contrast, liquid handing, and environmental control. Support many cellular assays Image an incredible range of assays with various user-changeable filter cubes, 1-100x objectives, environmental control, fluidics option, and many sample formats including atypical plates for 3D assays. Analyze images of more applications A selection of feature-rich turnkey application modules is available with MetaXpress software. For the development of novel assays, we offer an optional custom analysis module. Tailor the system to meet your needs The imager is a highly flexible solution, you can add or change many of the components as your research priorities change. Examples include enhance light engines and automation. Features Multiple imaging modes The system offers fluorescence, widefield, colorimetric, phase contrast, and brightfield label-free imaging. Upgradeable to confocal The system can be upgraded to include the proprietary AgileOptix technology for accurate 3D volumetric analyses. Wide dynamic range Low and high intensity signal quantification in a single image with >3 log dynamic range intensity detection. High speed image acquisition Using 4x magnification with a 1536-well plate, 225K wells per day can be acquired. Greater than a million wells per week can be imaged. Optional environmental control Temperature, humidity, and CO2 control for multi-day live-cell imaging or fast kinetic studies are available. Large magnification range Air and oil immersion objectives ranging from 1x to 100x are available for installation into the 4-position objective changer.
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Phenotypic Characterization Of Toxic Compound Effects On Cardiomyocytes Derived From Induced Pluripotent Stem Cells
Assess cardiotoxicity effects using automated imaging
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Evaluating Cell Cycle Inhibitors Using A Live Cell Assay
Evaluation of cell cycle inhibitors using live cell assay with ImageXpress Micro 4.
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BioassemblyBot 400: More Than A Bioprinter - Intelligent, Precise, And Scalable Automation Solution For 3D Biology
BioAssemblyBot 400 offers intelligent 3D biology automation. Integrates with ImageXpress Confocal HT.ai for advanced organoid workflows.
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Molecular Devices ImageXpress Micro 4 High-Content Imaging System Datasheet
The ImageXpress Micro 4 High-Content Imaging System is a versatile and efficient imaging solution for research purposes. It offers the option to upgrade to confocal imaging in the future and is compatible with a wide range of assays. The system allows for fast data acquisition and offers various research capabilities. Combined with MetaXpress software, it provides a complete solution for image interpretation and data analysis.
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Increase Accuracy And Efficiency Of Cytotoxicity Assessment Using The Earlytox Live/Dead Assay Kit And High-Content Imaging
This application note describes the use of the EarlyTox Live/Dead Assay Kit in conjunction with the ImageXpress Micro High-Content Imaging System & MetaXpress and high-content imaging system.
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Assessment Of Neurotoxicity And Neuronal Development Using Induced Pluripotent Stem Cell-Based Neurite Outgrowth Assay
This application note describes about the neurotoxicity & neuronal development by using pluripotent stem cell-based neurite outgrowth assay which evaluate & prioritize chemicals for their neurotoxicity potential.