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Biozen™ LC Columns

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From mAbs to Oligos, We Have You Covered

Phenomenex is committed to the development of novel chromatographic solutions that advance biopharmaceutical development. This rapidly-growing industry necessitates fit for purpose applications and innovative technologies to meet the expanding analytical challenges of the field.

Phenomenex columns and sample preparation solutions are designed to tackle the multi-faceted analytical needs of large molecule analysis, particularly in the area of biopharmaceutical analysis. Leveraging cutting-edge technology and expertise, our biopharmaceutical solutions provide tailored support for accurate and reliable results in this specialized field.

bioZen 2.6 µm Peptide Polar-C18, Nano Cartridge for SCIEX, 150 x 0.075 mm, Ea

bioZen 2.6 µm Peptide Polar-C18, Nano Cartridge for SCIEX, 150 x 0.075 mm, Ea

bioZen 2.6 µm Peptide Polar-C18, Nano Column, 150 x 0.075 mm, Dual SecurityLink, Ea

Biozen 1.8 µm dSEC-2, 200 Å, LC Column50 x 2.1 mm, Ea

Biozen 1.8 µm dSEC-2, 200 Å, LC Column50 x 2.1 mm, Ea

Biozen 1.8 µm dSEC-2, 200 Å, LC Column 150 x 2.1 mm, Ea

Biozen 1.8 µm dSEC-2, 200 Å, LC Column 150 x 2.1 mm, Ea

bioZen 1.7 µm Oligo, LC Column 50 X 2.1 mm, Ea

bioZen 1.7 µm Oligo, LC Column 50 X 2.1 mm, Ea

bioZen 2.6 µm Peptide PS-C18, Nano Column, 150 x 0.075 mm, Dual SecurityLink, Ea

bioZen 2.6 µm Peptide PS-C18, Nano Cartridge for SCIEX, 250 x 0.075 mm, Ea

bioZen 2.6 µm Peptide PS-C18, Nano Cartridge for SCIEX, 250 x 0.075 mm, Ea

bioZen 2.6 µm Peptide Polar-C18, Nano Column, 150 x 0.075 mm, fused-silica inlet/outlet, Ea

bioZen 2.6 µm Peptide Polar-C18, Nano Column, 150 x 0.075 mm, fused-silica inlet/outlet, Ea

bioZen 2.6 µm Peptide XB-C18, Nano Column, 250 x 0.075 mm, Dual SecurityLink, Ea

bioZen 2.6 µm Peptide PS-C18, Nano Cartridge for SCIEX, 150 x 0.075 mm, Ea

bioZen 2.6 µm Peptide PS-C18, Nano Cartridge for SCIEX, 150 x 0.075 mm, Ea

Five Advanced Particle Platforms

Biozen Technology

All five of the Biozen particle platforms were individually designed and built by Phenomenex to take advantage of integral levels of performance, ruggedness, and reproducibility for protein characterization applications. Individually, each platform differs in the proprietary processing techniques used to control particle size and morphology.

Inside Biozen BioTi Hardware

Biozen HPLC Bioti Hardware

A: UHPLC Pressure Rating

Allows for more experimental design space; room to increase flow rates for increased throughput

B: Better Controlled ID Versus PEEK Hardware

Improved column-to-column performance, providing more consistency and easier method validation

C: Biocompatible Titanium Liner

D: Improved Recovery and Peak Shape

Better column-to-column consistency, ease of use, and troubleshooting

E: Strong Stainless Steel Walls Help Prevent Movement Under Pressure

F: Biocompatible Titanium Frit

Biocompatible Flow Path with BioTi Hardware Keep your mind at ease knowing that we’ve minimized the need for priming with a new titanium infused biocompatible hardware and frit that doesn’t interfere with protein or peptide integrity! 4 Advanced Particle Platforms All four of the Biozen particle platforms were individually designed and built by Phenomenex to take advantage of integral levels of performance, ruggedness, and reproducibility for protein characterization applications. Individually, each platform differs in the proprietary processing techniques used to control particle size and morphology. Pore Controlled Technology Monosized Polymeric Non-Porous Core-Shell Technology Thermally Modified Fully Porous 8 Particle Chemistries ul> Biozen dSEC : 1.8 µm and 3 µm Biozen Intact XB-C8 : 3.6 µm Biozen WidePore C4 : 2.6 µm Biozen Glycan : 2.6 µm Biozen Oligo : 1.7 µm and 2.6 µm Biozen Peptide XB-C18 : 1.7 µm and 2.6 µm Biozen Peptide PS-C18 : 1.6 µm and 3 µm Biozen WCX : 6 µm Inside Biozen BioTi Hardware UHPLC Pressure Rating More experimental design space More experimental design space, with room to increase flow rates for increased throughput Better Controlled ID Versus PEEK Hardware Improved column-to-column performance, providing more consistency and easier method validation Improved Recovery and Peak Shape Better column-to-column consistency, ease of use, and troubleshooting Biocompatible Titanium Liner Biocompatible Titanium Frit Strong Stainless Steel Walls Help Prevent Movement Under Pressure Inside Biozen Particle Platforms Thermally Modified Fully Porous Through a proprietary thermal processing series of steps, we eliminate micropores and further improve consistency, column efficiency, inertness, ruggedness, and reproducibility. Core-Shell Technology Using sol-gel processing techniques that incorporate nano structuring technology, a durable, homogeneous porous shell is grown on a solid silica core. This highly optimized process combined with industry leading column packing technology produces highly reproducible columns that generate extremely high efficiencies and sensitivity. Monosized Polymeric Non-Porous Meticulously controlled monosized particle technology secures incredible particle consistency that leads to improved and reliable efficiency. This innovative non-porous particle serves as the perfect backbone for complex ion-exchange chemistries. Pore Controlled Technology The Biozen dSEC columns are packed with low pore volume silica coupled with a proprietary hydrophilic diol-type bonded surface chemistry that prevents the silica surface from interacting with protein samples.
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Unparalleled HPLC / UHPLC Inertness For Biologics
“Primed” to Help You! ... We’ve minimized the need for priming with a new titanium infused biocompatible hardware and frit that doesn’t interfere with protein or peptide integrity! ... ™ ...
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Biozen SEC Chromatographic Solution
The Biozen SEC chromatographic solution is a robust method for analyzing aggregates in biomolecules. It utilizes advanced SEC silica particle technology and surface chemistry to separate mAb fragments and high molecular weight forms.